null

SMILES: ONC(=O)[C@H](CNC(=O)c1ccc(OCc2ccnc(c2)-c2ccccc2)cc1)N1CCCCC1

InChI Key: InChIKey=HMKOPGQRIXEHTH-VWLOTQADSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 207966   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM207966 (US9266848, 4) Show SMILES ONC(=O)[C@H](CNC(=O)c1ccc(OCc2ccnc(c2)-c2ccccc2)cc1)N1CCCCC1 Show InChI InChI=1S/C27H30N4O4/c32-26(29-18-25(27(33)30-34)31-15-5-2-6-16-31)22-9-11-23(12-10-22)35-19-20-13-14-28-24(17-20)21-7-3-1-4-8-21/h1,3-4,7-14,17,25,34H,2,5-6,15-16,18-19H2,(H,29,32)(H,30,33)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	61	n/a	n/a	n/a	n/a	7.4	37
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The TACE enzyme is an internal production (carried out according to the publication Protein Eng Des Sel, 2006, 19, 155-161) and is added so as to hav...				US Patent US9266848 (2016) BindingDB Entry DOI: 10.7270/Q2TM78ZS
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM207966 (US9266848, 4) Show SMILES ONC(=O)[C@H](CNC(=O)c1ccc(OCc2ccnc(c2)-c2ccccc2)cc1)N1CCCCC1 Show InChI InChI=1S/C27H30N4O4/c32-26(29-18-25(27(33)30-34)31-15-5-2-6-16-31)22-9-11-23(12-10-22)35-19-20-13-14-28-24(17-20)21-7-3-1-4-8-21/h1,3-4,7-14,17,25,34H,2,5-6,15-16,18-19H2,(H,29,32)(H,30,33)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAM9 and ADAM10 according to the same protocol as that ...				US Patent US9266848 (2016) BindingDB Entry DOI: 10.7270/Q2TM78ZS
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 10 (Homo sapiens (Human))	BDBM207966 (US9266848, 4) Show SMILES ONC(=O)[C@H](CNC(=O)c1ccc(OCc2ccnc(c2)-c2ccccc2)cc1)N1CCCCC1 Show InChI InChI=1S/C27H30N4O4/c32-26(29-18-25(27(33)30-34)31-15-5-2-6-16-31)22-9-11-23(12-10-22)35-19-20-13-14-28-24(17-20)21-7-3-1-4-8-21/h1,3-4,7-14,17,25,34H,2,5-6,15-16,18-19H2,(H,29,32)(H,30,33)/t25-/m0/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAM9 and ADAM10 according to the same protocol as that ...				US Patent US9266848 (2016) BindingDB Entry DOI: 10.7270/Q2TM78ZS
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM207966 (US9266848, 4) Show SMILES ONC(=O)[C@H](CNC(=O)c1ccc(OCc2ccnc(c2)-c2ccccc2)cc1)N1CCCCC1 Show InChI InChI=1S/C27H30N4O4/c32-26(29-18-25(27(33)30-34)31-15-5-2-6-16-31)22-9-11-23(12-10-22)35-19-20-13-14-28-24(17-20)21-7-3-1-4-8-21/h1,3-4,7-14,17,25,34H,2,5-6,15-16,18-19H2,(H,29,32)(H,30,33)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAM9 and ADAM10 according to the same protocol as that ...				US Patent US9266848 (2016) BindingDB Entry DOI: 10.7270/Q2TM78ZS
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 9 (Homo sapiens (Human))	BDBM207966 (US9266848, 4) Show SMILES ONC(=O)[C@H](CNC(=O)c1ccc(OCc2ccnc(c2)-c2ccccc2)cc1)N1CCCCC1 Show InChI InChI=1S/C27H30N4O4/c32-26(29-18-25(27(33)30-34)31-15-5-2-6-16-31)22-9-11-23(12-10-22)35-19-20-13-14-28-24(17-20)21-7-3-1-4-8-21/h1,3-4,7-14,17,25,34H,2,5-6,15-16,18-19H2,(H,29,32)(H,30,33)/t25-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAM9 and ADAM10 according to the same protocol as that ...				US Patent US9266848 (2016) BindingDB Entry DOI: 10.7270/Q2TM78ZS
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM207966 (US9266848, 4) Show SMILES ONC(=O)[C@H](CNC(=O)c1ccc(OCc2ccnc(c2)-c2ccccc2)cc1)N1CCCCC1 Show InChI InChI=1S/C27H30N4O4/c32-26(29-18-25(27(33)30-34)31-15-5-2-6-16-31)22-9-11-23(12-10-22)35-19-20-13-14-28-24(17-20)21-7-3-1-4-8-21/h1,3-4,7-14,17,25,34H,2,5-6,15-16,18-19H2,(H,29,32)(H,30,33)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAM9 and ADAM10 according to the same protocol as that ...				US Patent US9266848 (2016) BindingDB Entry DOI: 10.7270/Q2TM78ZS
					More data for this Ligand-Target Pair