BDBM208624 US9266876, 91

SMILES: C[C@@H]1CN(CCN1C(=O)Cn1cnc2cccnc12)c1scnc1-c1nc2cc(F)c(F)cc2[nH]1

InChI Key: InChIKey=ASRHTNDMFVCZMJ-CYBMUJFWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 208624   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CXCR3A / G protein (Galpha(16)) (Homo sapiens (Human))	BDBM208624 (US9266876, 91) Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1cnc2cccnc12)c1scnc1-c1nc2cc(F)c(F)cc2[nH]1 Show InChI InChI=1S/C23H20F2N8OS/c1-13-9-31(5-6-33(13)19(34)10-32-11-27-16-3-2-4-26-22(16)32)23-20(28-12-35-23)21-29-17-7-14(24)15(25)8-18(17)30-21/h2-4,7-8,11-13H,5-6,9-10H2,1H3,(H,29,30)/t13-/m1/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.4	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				US Patent US9266876 (2016) BindingDB Entry DOI: 10.7270/Q2DB80NB
					More data for this Ligand-Target Pair