BDBM208676 US9266876, 143

SMILES: C[C@@H]1CN(CCN1C(=O)Cn1cc(Cl)c2cccnc12)c1scnc1-c1nc2ccccc2[nH]1

InChI Key: InChIKey=JTYXVQCIHWUUHK-OAHLLOKOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 208676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CXCR3A / G protein (Galpha(16)) (Homo sapiens (Human))	BDBM208676 (US9266876, 143) Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1cc(Cl)c2cccnc12)c1scnc1-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C24H22ClN7OS/c1-15-11-30(24-21(27-14-34-24)22-28-18-6-2-3-7-19(18)29-22)9-10-32(15)20(33)13-31-12-17(25)16-5-4-8-26-23(16)31/h2-8,12,14-15H,9-11,13H2,1H3,(H,28,29)/t15-/m1/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				US Patent US9266876 (2016) BindingDB Entry DOI: 10.7270/Q2DB80NB
					More data for this Ligand-Target Pair