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SMILES: C[C@@H]1CN(CCN1C(=O)Cn1cnc2cccnc12)c1sc(nc1-c1nc2cc(OCCO)ccc2[nH]1)C(F)(F)F

InChI Key: InChIKey=CYLSDQBKJIONGY-OAHLLOKOSA-N

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 208697   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 3/Guanine nucleotide-binding protein subunit alpha-15


(Homo sapiens (Human))		BDBM208697
PNG
(US9266876, 164)
Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1cnc2cccnc12)c1sc(nc1-c1nc2cc(OCCO)ccc2[nH]1)C(F)(F)F
Show InChI InChI=1S/C26H25F3N8O3S/c1-15-12-35(7-8-37(15)20(39)13-36-14-31-18-3-2-6-30-23(18)36)24-21(34-25(41-24)26(27,28)29)22-32-17-5-4-16(40-10-9-38)11-19(17)33-22/h2-6,11,14-15,38H,7-10,12-13H2,1H3,(H,32,33)/t15-/m1/s1
UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/a7.437



Actelion Pharmaceuticals Ltd.

US Patent


Assay Description
The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...

US Patent US9266876 (2016)


BindingDB Entry DOI: 10.7270/Q2DB80NB
More data for this
Ligand-Target Pair