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SMILES: C[C@@H]1CN(CCN1C(=O)Cn1cnc2cccnc12)c1sc(nc1-c1nc2cncnc2[nH]1)C(F)(F)F

InChI Key: InChIKey=VANOQPQHNBVXJW-GFCCVEGCSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 208704   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 3/Guanine nucleotide-binding protein subunit alpha-15


(Homo sapiens (Human))		BDBM208704
PNG
(US9266876, 171)
Show SMILES C[C@@H]1CN(CCN1C(=O)Cn1cnc2cccnc12)c1sc(nc1-c1nc2cncnc2[nH]1)C(F)(F)F
Show InChI InChI=1S/C22H19F3N10OS/c1-12-8-33(5-6-35(12)15(36)9-34-11-29-13-3-2-4-27-19(13)34)20-16(31-21(37-20)22(23,24)25)18-30-14-7-26-10-28-17(14)32-18/h2-4,7,10-12H,5-6,8-9H2,1H3,(H,26,28,30,32)/t12-/m1/s1
UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/a7.437



Actelion Pharmaceuticals Ltd.

US Patent


Assay Description
The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...

US Patent US9266876 (2016)


BindingDB Entry DOI: 10.7270/Q2DB80NB
More data for this
Ligand-Target Pair