BDBM208759 US9266876, 226

SMILES: FC(F)(F)c1nc(-c2nc3ccccc3[nH]2)c(s1)N1CCN(CC1)C(=O)Cn1cnc2cccnc12

InChI Key: InChIKey=FZRSFOKYQJRWAB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 208759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CXCR3A / G protein (Galpha(16)) (Homo sapiens (Human))	BDBM208759 (US9266876, 226) Show SMILES FC(F)(F)c1nc(-c2nc3ccccc3[nH]2)c(s1)N1CCN(CC1)C(=O)Cn1cnc2cccnc12 Show InChI InChI=1S/C23H19F3N8OS/c24-23(25,26)22-31-18(19-29-14-4-1-2-5-15(14)30-19)21(36-22)33-10-8-32(9-11-33)17(35)12-34-13-28-16-6-3-7-27-20(16)34/h1-7,13H,8-12H2,(H,29,30)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	37
Actelion Pharmaceuticals Ltd. US Patent					Assay Description The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...				US Patent US9266876 (2016) BindingDB Entry DOI: 10.7270/Q2DB80NB
					More data for this Ligand-Target Pair