BDBM208982 US9233167, a-6-mPEG1-O-Morphine

SMILES: COCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45

InChI Key: InChIKey=FBDRANYVHASQNW-WICKCUDESA-N

Data: 3 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 208982   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM208982 (US9233167, a-6-mPEG1-O-Morphine) Show SMILES COCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:17:25:8:23.21.22,13:12:8:23.21.22| Show InChI InChI=1S/C20H27NO5/c1-21-8-7-19-16-12-3-4-13(22)17(16)26-18(19)14(25-10-9-24-2)5-6-20(19,23)15(21)11-12/h3-4,14-15,18,22-23H,5-11H2,1-2H3/t14-,15?,18-,19-,20+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	15.7	-10.6	n/a	n/a	n/a	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM208982 (US9233167, a-6-mPEG1-O-Morphine) Show SMILES COCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:17:25:8:23.21.22,13:12:8:23.21.22| Show InChI InChI=1S/C20H27NO5/c1-21-8-7-19-16-12-3-4-13(22)17(16)26-18(19)14(25-10-9-24-2)5-6-20(19,23)15(21)11-12/h3-4,14-15,18,22-23H,5-11H2,1-2H3/t14-,15?,18-,19-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	445	-8.66	n/a	n/a	n/a	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM208982 (US9233167, a-6-mPEG1-O-Morphine) Show SMILES COCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:17:25:8:23.21.22,13:12:8:23.21.22| Show InChI InChI=1S/C20H27NO5/c1-21-8-7-19-16-12-3-4-13(22)17(16)26-18(19)14(25-10-9-24-2)5-6-20(19,23)15(21)11-12/h3-4,14-15,18,22-23H,5-11H2,1-2H3/t14-,15?,18-,19-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.72E+3	-7.59	n/a	n/a	n/a	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM208982 (US9233167, a-6-mPEG1-O-Morphine) Show SMILES COCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:17:25:8:23.21.22,13:12:8:23.21.22| Show InChI InChI=1S/C20H27NO5/c1-21-8-7-19-16-12-3-4-13(22)17(16)26-18(19)14(25-10-9-24-2)5-6-20(19,23)15(21)11-12/h3-4,14-15,18,22-23H,5-11H2,1-2H3/t14-,15?,18-,19-,20+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	85	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, suspensions of cells expressing either the mu, kappa or delta opioid receptors were prepared in buffer containing 0.5 mM isobutyl-methyl xan...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM208982 (US9233167, a-6-mPEG1-O-Morphine) Show SMILES COCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:17:25:8:23.21.22,13:12:8:23.21.22| Show InChI InChI=1S/C20H27NO5/c1-21-8-7-19-16-12-3-4-13(22)17(16)26-18(19)14(25-10-9-24-2)5-6-20(19,23)15(21)11-12/h3-4,14-15,18,22-23H,5-11H2,1-2H3/t14-,15?,18-,19-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.19E+3	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, suspensions of cells expressing either the mu, kappa or delta opioid receptors were prepared in buffer containing 0.5 mM isobutyl-methyl xan...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair