null

SMILES: COCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45

InChI Key: InChIKey=PNZNYWUSPRKEKE-TZNCDMKYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 208985   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM208985 (US9233167, a-6-mPEG4-O-Morphine) Show SMILES COCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:26:34:17:32.30.31,22:21:17:32.30.31| Show InChI InChI=1S/C26H39NO8/c1-27-8-7-25-22-18-3-4-19(28)23(22)35-24(25)20(5-6-26(25,29)21(27)17-18)34-16-15-33-14-13-32-12-11-31-10-9-30-2/h3-4,20-21,24,28-29H,5-17H2,1-2H3/t20-,21?,24-,25-,26+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	23.1	-10.4	n/a	n/a	n/a	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM208985 (US9233167, a-6-mPEG4-O-Morphine) Show SMILES COCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:26:34:17:32.30.31,22:21:17:32.30.31| Show InChI InChI=1S/C26H39NO8/c1-27-8-7-25-22-18-3-4-19(28)23(22)35-24(25)20(5-6-26(25,29)21(27)17-18)34-16-15-33-14-13-32-12-11-31-10-9-30-2/h3-4,20-21,24,28-29H,5-17H2,1-2H3/t20-,21?,24-,25-,26+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	439	-8.67	n/a	n/a	n/a	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM208985 (US9233167, a-6-mPEG4-O-Morphine) Show SMILES COCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:26:34:17:32.30.31,22:21:17:32.30.31| Show InChI InChI=1S/C26H39NO8/c1-27-8-7-25-22-18-3-4-19(28)23(22)35-24(25)20(5-6-26(25,29)21(27)17-18)34-16-15-33-14-13-32-12-11-31-10-9-30-2/h3-4,20-21,24,28-29H,5-17H2,1-2H3/t20-,21?,24-,25-,26+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.36E+3	-7.46	n/a	n/a	n/a	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM208985 (US9233167, a-6-mPEG4-O-Morphine) Show SMILES COCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:26:34:17:32.30.31,22:21:17:32.30.31| Show InChI InChI=1S/C26H39NO8/c1-27-8-7-25-22-18-3-4-19(28)23(22)35-24(25)20(5-6-26(25,29)21(27)17-18)34-16-15-33-14-13-32-12-11-31-10-9-30-2/h3-4,20-21,24,28-29H,5-17H2,1-2H3/t20-,21?,24-,25-,26+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	128	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, suspensions of cells expressing either the mu, kappa or delta opioid receptors were prepared in buffer containing 0.5 mM isobutyl-methyl xan...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM208985 (US9233167, a-6-mPEG4-O-Morphine) Show SMILES COCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:26:34:17:32.30.31,22:21:17:32.30.31| Show InChI InChI=1S/C26H39NO8/c1-27-8-7-25-22-18-3-4-19(28)23(22)35-24(25)20(5-6-26(25,29)21(27)17-18)34-16-15-33-14-13-32-12-11-31-10-9-30-2/h3-4,20-21,24,28-29H,5-17H2,1-2H3/t20-,21?,24-,25-,26+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.09E+3	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, suspensions of cells expressing either the mu, kappa or delta opioid receptors were prepared in buffer containing 0.5 mM isobutyl-methyl xan...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair