BDBM208988 US9233167, a-6-mPEG7-O-Morphine

SMILES: COCCOCCOCCOCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45

InChI Key: InChIKey=HSENMLAGELTHPF-UEECTYCKSA-N

Data: 3 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 208988   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM208988 (US9233167, a-6-mPEG7-O-Morphine) Show SMILES COCCOCCOCCOCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:35:43:26:41.39.40,31:30:26:41.39.40| Show InChI InChI=1S/C32H51NO11/c1-33-8-7-31-28-24-3-4-25(34)29(28)44-30(31)26(5-6-32(31,35)27(33)23-24)43-22-21-42-20-19-41-18-17-40-16-15-39-14-13-38-12-11-37-10-9-36-2/h3-4,26-27,30,34-35H,5-23H2,1-2H3/t26-,27?,30-,31-,32+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	56.9	-9.88	n/a	n/a	n/a	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM208988 (US9233167, a-6-mPEG7-O-Morphine) Show SMILES COCCOCCOCCOCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:35:43:26:41.39.40,31:30:26:41.39.40| Show InChI InChI=1S/C32H51NO11/c1-33-8-7-31-28-24-3-4-25(34)29(28)44-30(31)26(5-6-32(31,35)27(33)23-24)43-22-21-42-20-19-41-18-17-40-16-15-39-14-13-38-12-11-37-10-9-36-2/h3-4,26-27,30,34-35H,5-23H2,1-2H3/t26-,27?,30-,31-,32+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	670	-8.42	n/a	n/a	n/a	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM208988 (US9233167, a-6-mPEG7-O-Morphine) Show SMILES COCCOCCOCCOCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:35:43:26:41.39.40,31:30:26:41.39.40| Show InChI InChI=1S/C32H51NO11/c1-33-8-7-31-28-24-3-4-25(34)29(28)44-30(31)26(5-6-32(31,35)27(33)23-24)43-22-21-42-20-19-41-18-17-40-16-15-39-14-13-38-12-11-37-10-9-36-2/h3-4,26-27,30,34-35H,5-23H2,1-2H3/t26-,27?,30-,31-,32+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.59E+3	-7.62	n/a	n/a	n/a	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM208988 (US9233167, a-6-mPEG7-O-Morphine) Show SMILES COCCOCCOCCOCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:35:43:26:41.39.40,31:30:26:41.39.40| Show InChI InChI=1S/C32H51NO11/c1-33-8-7-31-28-24-3-4-25(34)29(28)44-30(31)26(5-6-32(31,35)27(33)23-24)43-22-21-42-20-19-41-18-17-40-16-15-39-14-13-38-12-11-37-10-9-36-2/h3-4,26-27,30,34-35H,5-23H2,1-2H3/t26-,27?,30-,31-,32+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	508	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, suspensions of cells expressing either the mu, kappa or delta opioid receptors were prepared in buffer containing 0.5 mM isobutyl-methyl xan...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM208988 (US9233167, a-6-mPEG7-O-Morphine) Show SMILES COCCOCCOCCOCCOCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:35:43:26:41.39.40,31:30:26:41.39.40| Show InChI InChI=1S/C32H51NO11/c1-33-8-7-31-28-24-3-4-25(34)29(28)44-30(31)26(5-6-32(31,35)27(33)23-24)43-22-21-42-20-19-41-18-17-40-16-15-39-14-13-38-12-11-37-10-9-36-2/h3-4,26-27,30,34-35H,5-23H2,1-2H3/t26-,27?,30-,31-,32+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.24E+3	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, suspensions of cells expressing either the mu, kappa or delta opioid receptors were prepared in buffer containing 0.5 mM isobutyl-methyl xan...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair