BDBM208992 US9233167, a-6-mPEG3-O-Hydroxycodone

SMILES: COCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(OC)c5O[C@@H]1[C@]2(CCN3C)c45

InChI Key: InChIKey=XHEXWSCWJOOGNE-VQJSZXDJSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 208992   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM208992 (US9233167, a-6-mPEG3-O-Hydroxycodone) Show SMILES COCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(OC)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:24:32:14:30.28.29,19:18:14:30.28.29| Show InChI InChI=1S/C25H37NO7/c1-26-9-8-24-21-17-4-5-18(29-3)22(21)33-23(24)19(6-7-25(24,27)20(26)16-17)32-15-14-31-13-12-30-11-10-28-2/h4-5,19-20,23,27H,6-16H2,1-3H3/t19-,20?,23-,24-,25+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	775	-8.33	n/a	n/a	n/a	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM208992 (US9233167, a-6-mPEG3-O-Hydroxycodone) Show SMILES COCCOCCOCCO[C@H]1CC[C@@]2(O)C3Cc4ccc(OC)c5O[C@@H]1[C@]2(CCN3C)c45 |r,TLB:24:32:14:30.28.29,19:18:14:30.28.29| Show InChI InChI=1S/C25H37NO7/c1-26-9-8-24-21-17-4-5-18(29-3)22(21)33-23(24)19(6-7-25(24,27)20(26)16-17)32-15-14-31-13-12-30-11-10-28-2/h4-5,19-20,23,27H,6-16H2,1-3H3/t19-,20?,23-,24-,25+/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.83E+3	n/a	n/a	n/a	25
Nektar Therapeutics US Patent					Assay Description Briefly, suspensions of cells expressing either the mu, kappa or delta opioid receptors were prepared in buffer containing 0.5 mM isobutyl-methyl xan...				US Patent US9233167 (2016) BindingDB Entry DOI: 10.7270/Q25T3J97
					More data for this Ligand-Target Pair