BDBM209025 US9243038, 5a (cis olefin)::US9243038, 5b (trans olefin)

SMILES: NC(=O)[C@@H]1CCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC(=O)[C@H](CC2CCCCC2)NC(=O)[C@H](CC2CC2)NC(=O)\C=C\C(=O)N1

InChI Key: InChIKey=FFJICIDEVUQXRQ-ZCHKFXGQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
insulin-degrading enzyme isoform 1 precursor (Homo sapiens (Human))	BDBM209025 (US9243038, 5a (cis olefin) | US9243038, 5b (trans ...) Show SMILES NC(=O)[C@@H]1CCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC(=O)[C@H](CC2CCCCC2)NC(=O)[C@H](CC2CC2)NC(=O)\C=C\C(=O)N1 |r,t:53| Show InChI InChI=1S/C41H52N6O7/c42-38(51)31-13-7-8-22-43-39(52)32(24-28-16-18-30(19-17-28)37(50)29-11-5-2-6-12-29)46-41(54)34(23-26-9-3-1-4-10-26)47-40(53)33(25-27-14-15-27)45-36(49)21-20-35(48)44-31/h2,5-6,11-12,16-21,26-27,31-34H,1,3-4,7-10,13-15,22-25H2,(H2,42,51)(H,43,52)(H,44,48)(H,45,49)(H,46,54)(H,47,53)/b21-20+/t31-,32+,33-,34-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
President and Fellows of Harvard College US Patent					Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...				US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV
					More data for this Ligand-Target Pair
insulin-degrading enzyme isoform 1 precursor (Homo sapiens (Human))	BDBM209025 (US9243038, 5a (cis olefin) | US9243038, 5b (trans ...) Show SMILES NC(=O)[C@@H]1CCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC(=O)[C@H](CC2CCCCC2)NC(=O)[C@H](CC2CC2)NC(=O)\C=C\C(=O)N1 |r,t:53| Show InChI InChI=1S/C41H52N6O7/c42-38(51)31-13-7-8-22-43-39(52)32(24-28-16-18-30(19-17-28)37(50)29-11-5-2-6-12-29)46-41(54)34(23-26-9-3-1-4-10-26)47-40(53)33(25-27-14-15-27)45-36(49)21-20-35(48)44-31/h2,5-6,11-12,16-21,26-27,31-34H,1,3-4,7-10,13-15,22-25H2,(H2,42,51)(H,43,52)(H,44,48)(H,45,49)(H,46,54)(H,47,53)/b21-20+/t31-,32+,33-,34-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
President and Fellows of Harvard College US Patent					Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...				US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV
					More data for this Ligand-Target Pair