BDBM209039 US9243038, 12

SMILES: CC(C)C(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NCCCC[C@H](NC(=O)\C=C\C(=O)N[C@@H](CCC(N)=O)C(N)=O)C(N)=O

InChI Key: InChIKey=PGWURNMKMFVFGE-OQTQFXIPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 209039   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
insulin-degrading enzyme isoform 1 precursor (Homo sapiens (Human))	BDBM209039 (US9243038, 12) Show SMILES CC(C)C(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NCCCC[C@H](NC(=O)\C=C\C(=O)N[C@@H](CCC(N)=O)C(N)=O)C(N)=O |r| Show InChI InChI=1S/C35H45N7O8/c1-21(2)34(49)42-27(20-22-11-13-24(14-12-22)31(46)23-8-4-3-5-9-23)35(50)39-19-7-6-10-25(32(37)47)40-29(44)17-18-30(45)41-26(33(38)48)15-16-28(36)43/h3-5,8-9,11-14,17-18,21,25-27H,6-7,10,15-16,19-20H2,1-2H3,(H2,36,43)(H2,37,47)(H2,38,48)(H,39,50)(H,40,44)(H,41,45)(H,42,49)/b18-17+/t25-,26-,27+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
President and Fellows of Harvard College US Patent					Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...				US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV
					More data for this Ligand-Target Pair