BDBM209039 US9243038, 12
SMILES: CC(C)C(=O)N[C@H](Cc1ccc(cc1)C(=O)c1ccccc1)C(=O)NCCCC[C@H](NC(=O)\C=C\C(=O)N[C@@H](CCC(N)=O)C(N)=O)C(N)=O
InChI Key: InChIKey=PGWURNMKMFVFGE-OQTQFXIPSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
insulin-degrading enzyme isoform 1 precursor (Homo sapiens (Human)) | BDBM209039 (US9243038, 12) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
President and Fellows of Harvard College US Patent | Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o... | US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV | |||||||||||
More data for this Ligand-Target Pair |