BDBM209047 US9243038, 24

SMILES: NC(=O)CC[C@@H]1NC(=O)\C=C/C(=O)NNCCCCC(NCCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC(=O)[C@H](CC2CCCCC2)NC1=O)C(N)=O

InChI Key: InChIKey=WKOBFAHFWUJFPE-HKVCMJQBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 209047   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-degrading enzyme (Homo sapiens (Human))	BDBM209047 (US9243038, 24) Show SMILES NC(=O)CC[C@@H]1NC(=O)\C=C/C(=O)NNCCCCC(NCCCCNC(=O)[C@@H](Cc2ccc(cc2)C(=O)c2ccccc2)NC(=O)[C@H](CC2CCCCC2)NC1=O)C(N)=O |r,c:9| Show InChI InChI=1S/C44H61N9O8/c45-37(54)21-20-34-43(60)52-36(27-29-11-3-1-4-12-29)44(61)51-35(28-30-16-18-32(19-17-30)40(57)31-13-5-2-6-14-31)42(59)48-25-10-9-24-47-33(41(46)58)15-7-8-26-49-53-39(56)23-22-38(55)50-34/h2,5-6,13-14,16-19,22-23,29,33-36,47,49H,1,3-4,7-12,15,20-21,24-28H2,(H2,45,54)(H2,46,58)(H,48,59)(H,50,55)(H,51,61)(H,52,60)(H,53,56)/b23-22-/t33?,34-,35+,36-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
President and Fellows of Harvard College US Patent					Assay Description Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...				US Patent US9243038 (2016) BindingDB Entry DOI: 10.7270/Q2MW2FZV
					More data for this Ligand-Target Pair