BDBM209302 US9266883, 60

SMILES: OCc1cc2CCCN(C(=O)Nc3cc(OCC(O)CCCl)c(cn3)C#N)c2nc1C=O

InChI Key: InChIKey=WFDCPWMWPOCEFP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 209302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (FGFR4) (Homo sapiens (Human))	BDBM209302 (US9266883, 60) Show SMILES OCc1cc2CCCN(C(=O)Nc3cc(OCC(O)CCCl)c(cn3)C#N)c2nc1C=O Show InChI InChI=1S/C21H22ClN5O5/c22-4-3-16(30)12-32-18-7-19(24-9-15(18)8-23)26-21(31)27-5-1-2-13-6-14(10-28)17(11-29)25-20(13)27/h6-7,9,11,16,28,30H,1-5,10,12H2,(H,24,26,31)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair