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SMILES: COCCNc1cc(NC(=O)N2CCCc3cc(CN4CCS(=O)(=O)CC4=O)c(C=O)nc23)ncc1C#N

InChI Key: InChIKey=ITGMWEIJHHGQAV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 209351   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fibroblast growth factor receptor 4 [388-802]


(Homo sapiens (Human))		BDBM209351
PNG
(US9266883, 150)
Show SMILES COCCNc1cc(NC(=O)N2CCCc3cc(CN4CCS(=O)(=O)CC4=O)c(C=O)nc23)ncc1C#N
Show InChI InChI=1S/C24H27N7O6S/c1-37-7-4-26-19-10-21(27-12-18(19)11-25)29-24(34)31-5-2-3-16-9-17(20(14-32)28-23(16)31)13-30-6-8-38(35,36)15-22(30)33/h9-10,12,14H,2-8,13,15H2,1H3,(H2,26,27,29,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.20n/an/an/an/a7.530



Novartis AG

US Patent


Assay Description
Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...

US Patent US9266883 (2016)


BindingDB Entry DOI: 10.7270/Q2CC0ZGP
More data for this
Ligand-Target Pair