BDBM209354 US9266883, 188

SMILES: CN(Cc1cc2CCCN(C(=O)Nc3cc(NCCOC(F)(F)F)c(cn3)C#N)c2nc1C=O)C(C)=O

InChI Key: InChIKey=VYBADZNHKZIAQI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 209354   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (FGFR4) (Homo sapiens (Human))	BDBM209354 (US9266883, 188) Show SMILES CN(Cc1cc2CCCN(C(=O)Nc3cc(NCCOC(F)(F)F)c(cn3)C#N)c2nc1C=O)C(C)=O Show InChI InChI=1S/C23H24F3N7O4/c1-14(35)32(2)12-16-8-15-4-3-6-33(21(15)30-19(16)13-34)22(36)31-20-9-18(17(10-27)11-29-20)28-5-7-37-23(24,25)26/h8-9,11,13H,3-7,12H2,1-2H3,(H2,28,29,31,36)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair