BDBM209544 US9271969, 32

SMILES: Cc1ccccc1NC(=O)c1cn2cc(ccc2n1)-c1ccc(cc1)C1CC[C@H](CC(O)=O)CC1

InChI Key: InChIKey=NLUCDPHKIRNBFD-ABOQPKSFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209544   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM209544 (US9271969, 32) Show SMILES Cc1ccccc1NC(=O)c1cn2cc(ccc2n1)-c1ccc(cc1)C1CC[C@H](CC(O)=O)CC1 |r,wD:28.32,(-8.9,5.08,;-9.67,3.75,;-11.21,3.75,;-11.98,2.41,;-11.21,1.08,;-9.67,1.08,;-8.9,2.41,;-7.36,2.41,;-6.59,1.08,;-7.36,-.25,;-5.06,1.08,;-4.15,-.17,;-2.69,.31,;-1.35,-.46,;-.02,.31,;-.02,1.85,;-1.35,2.62,;-2.69,1.85,;-4.15,2.33,;1.32,-.46,;1.32,-2,;2.65,-2.77,;3.98,-2,;3.98,-.46,;2.65,.31,;5.32,-2.77,;6.65,-2,;7.98,-2.77,;7.98,-4.31,;9.32,-5.08,;10.65,-4.31,;11.98,-5.08,;10.65,-2.77,;6.65,-5.08,;5.32,-4.31,)| Show InChI InChI=1S/C29H29N3O3/c1-19-4-2-3-5-25(19)31-29(35)26-18-32-17-24(14-15-27(32)30-26)23-12-10-22(11-13-23)21-8-6-20(7-9-21)16-28(33)34/h2-5,10-15,17-18,20-21H,6-9,16H2,1H3,(H,31,35)(H,33,34)/t20-,21?	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.4	25
KAINOS MEDICINE, INC. US Patent					Assay Description  Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ...				US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (DGAT1) (Homo sapiens (Human))	BDBM209544 (US9271969, 32) Show SMILES Cc1ccccc1NC(=O)c1cn2cc(ccc2n1)-c1ccc(cc1)C1CC[C@H](CC(O)=O)CC1 |r,wD:28.32,(-8.9,5.08,;-9.67,3.75,;-11.21,3.75,;-11.98,2.41,;-11.21,1.08,;-9.67,1.08,;-8.9,2.41,;-7.36,2.41,;-6.59,1.08,;-7.36,-.25,;-5.06,1.08,;-4.15,-.17,;-2.69,.31,;-1.35,-.46,;-.02,.31,;-.02,1.85,;-1.35,2.62,;-2.69,1.85,;-4.15,2.33,;1.32,-.46,;1.32,-2,;2.65,-2.77,;3.98,-2,;3.98,-.46,;2.65,.31,;5.32,-2.77,;6.65,-2,;7.98,-2.77,;7.98,-4.31,;9.32,-5.08,;10.65,-4.31,;11.98,-5.08,;10.65,-2.77,;6.65,-5.08,;5.32,-4.31,)| Show InChI InChI=1S/C29H29N3O3/c1-19-4-2-3-5-25(19)31-29(35)26-18-32-17-24(14-15-27(32)30-26)23-12-10-22(11-13-23)21-8-6-20(7-9-21)16-28(33)34/h2-5,10-15,17-18,20-21H,6-9,16H2,1H3,(H,31,35)(H,33,34)/t20-,21?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.4	25
KAINOS MEDICINE, INC. US Patent					Assay Description  Assay buffer [20 mM HEPES (pH 7.4), 100 mM MgCl2 and 0.04% bovine serum albumin (BSA)] containing 500 uM of enzyme substrate (didecanoyl glycerol) ...				US Patent US9271969 (2016) BindingDB Entry DOI: 10.7270/Q2057DS8
					More data for this Ligand-Target Pair