BDBM209853 US9273052, 1::US9566277, 1
SMILES: Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCn2c(C1)nnc2C(F)(F)F
InChI Key: InChIKey=YKRHDVRJUDSJQC-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human)) | BDBM209853 (US9273052, 1 | US9566277, 1) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | 25 |
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent | Assay Description he assay described below is to determine the activity of the compounds of the present invention for inhibiting the enzyme activity of PARP by using t... | US Patent US9566277 (2017) BindingDB Entry DOI: 10.7270/Q2Q24279 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human)) | BDBM209853 (US9273052, 1 | US9566277, 1) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | 25 |
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent | Assay Description The tested compounds were dissolved in dimethylsulfoxide and then diluted with 1x buffer to the concentration desired in the experiment. 25 uL of a 2... | US Patent US9273052 (2016) BindingDB Entry DOI: 10.7270/Q2Z60MWG | |||||||||||
More data for this Ligand-Target Pair |