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SMILES: FC(F)(F)COc1nc(ccc1C1CC1)C(=O)NC(c1ccccn1)C(F)(F)F

InChI Key: InChIKey=DCNVVRADNMZNIR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 210616   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM210616 (US9290451, 302) Show SMILES FC(F)(F)COc1nc(ccc1C1CC1)C(=O)NC(c1ccccn1)C(F)(F)F Show InChI InChI=1S/C18H15F6N3O2/c19-17(20,21)9-29-16-11(10-4-5-10)6-7-13(26-16)15(28)27-14(18(22,23)24)12-3-1-2-8-25-12/h1-3,6-8,10,14H,4-5,9H2,(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9290451 (2016) BindingDB Entry DOI: 10.7270/Q20Z724J
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM210616 (US9290451, 302) Show SMILES FC(F)(F)COc1nc(ccc1C1CC1)C(=O)NC(c1ccccn1)C(F)(F)F Show InChI InChI=1S/C18H15F6N3O2/c19-17(20,21)9-29-16-11(10-4-5-10)6-7-13(26-16)15(28)27-14(18(22,23)24)12-3-1-2-8-25-12/h1-3,6-8,10,14H,4-5,9H2,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	587	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9290451 (2016) BindingDB Entry DOI: 10.7270/Q20Z724J
					More data for this Ligand-Target Pair