BDBM21071 4-(4-aminophenyl)-1,2-benzoxazol-3-amine::Aminobenzoisoxazole, 8

SMILES: Nc1noc2cccc(-c3ccc(N)cc3)c12

InChI Key: InChIKey=RBVHBTLBKSWXCF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21071   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM21071 (4-(4-aminophenyl)-1,2-benzoxazol-3-amine | Aminobe...) Show SMILES Nc1noc2cccc(-c3ccc(N)cc3)c12 Show InChI InChI=1S/C13H11N3O/c14-9-6-4-8(5-7-9)10-2-1-3-11-12(10)13(15)16-17-11/h1-7H,14H2,(H2,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...				J Med Chem 51: 1231-41 (2008) Article DOI: 10.1021/jm701096v BindingDB Entry DOI: 10.7270/Q2HX19Z7
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM21071 (4-(4-aminophenyl)-1,2-benzoxazol-3-amine | Aminobe...) Show SMILES Nc1noc2cccc(-c3ccc(N)cc3)c12 Show InChI InChI=1S/C13H11N3O/c14-9-6-4-8(5-7-9)10-2-1-3-11-12(10)13(15)16-17-11/h1-7H,14H2,(H2,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...				J Med Chem 51: 1231-41 (2008) Article DOI: 10.1021/jm701096v BindingDB Entry DOI: 10.7270/Q2HX19Z7
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM21071 (4-(4-aminophenyl)-1,2-benzoxazol-3-amine | Aminobe...) Show SMILES Nc1noc2cccc(-c3ccc(N)cc3)c12 Show InChI InChI=1S/C13H11N3O/c14-9-6-4-8(5-7-9)10-2-1-3-11-12(10)13(15)16-17-11/h1-7H,14H2,(H2,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.88E+4	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...				J Med Chem 51: 1231-41 (2008) Article DOI: 10.1021/jm701096v BindingDB Entry DOI: 10.7270/Q2HX19Z7
					More data for this Ligand-Target Pair