BDBM21072 Aminobenzoisoxazole, 9::[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]urea

SMILES: NC(=O)Nc1ccc(cc1)-c1cccc2onc(N)c12

InChI Key: InChIKey=QKEZZTSUDGCSDM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM21072 (Aminobenzoisoxazole, 9 | [4-(3-amino-1,2-benzoxazo...) Show SMILES NC(=O)Nc1ccc(cc1)-c1cccc2onc(N)c12 Show InChI InChI=1S/C14H12N4O2/c15-13-12-10(2-1-3-11(12)20-18-13)8-4-6-9(7-5-8)17-14(16)19/h1-7H,(H2,15,18)(H3,16,17,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...				J Med Chem 51: 1231-41 (2008) Article DOI: 10.1021/jm701096v BindingDB Entry DOI: 10.7270/Q2HX19Z7
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM21072 (Aminobenzoisoxazole, 9 | [4-(3-amino-1,2-benzoxazo...) Show SMILES NC(=O)Nc1ccc(cc1)-c1cccc2onc(N)c12 Show InChI InChI=1S/C14H12N4O2/c15-13-12-10(2-1-3-11(12)20-18-13)8-4-6-9(7-5-8)17-14(16)19/h1-7H,(H2,15,18)(H3,16,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...				J Med Chem 51: 1231-41 (2008) Article DOI: 10.1021/jm701096v BindingDB Entry DOI: 10.7270/Q2HX19Z7
					More data for this Ligand-Target Pair
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM21072 (Aminobenzoisoxazole, 9 | [4-(3-amino-1,2-benzoxazo...) Show SMILES NC(=O)Nc1ccc(cc1)-c1cccc2onc(N)c12 Show InChI InChI=1S/C14H12N4O2/c15-13-12-10(2-1-3-11(12)20-18-13)8-4-6-9(7-5-8)17-14(16)19/h1-7H,(H2,15,18)(H3,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	619	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...				J Med Chem 51: 1231-41 (2008) Article DOI: 10.1021/jm701096v BindingDB Entry DOI: 10.7270/Q2HX19Z7
					More data for this Ligand-Target Pair