null

SMILES: CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(C2)c2ncnc(OCC(C)(C)O)c2Cl)cc1

InChI Key: InChIKey=OIGITXUTCBWDJT-KPMSDPLLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 212626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 [129-967] (Homo sapiens (Human))	BDBM212626 (BDBM212745 | US9278954, 1.17) Show SMILES CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(C2)c2ncnc(OCC(C)(C)O)c2Cl)cc1 |r| Show InChI InChI=1S/C23H31ClN4O4/c1-5-25-21(29)15(2)16-6-8-17(9-7-16)32-18-10-11-28(12-18)20-19(24)22(27-14-26-20)31-13-23(3,4)30/h6-9,14-15,18,30H,5,10-13H2,1-4H3,(H,25,29)/t15?,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	272	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 [129-967] (Homo sapiens (Human))	BDBM212626 (BDBM212745 | US9278954, 1.17) Show SMILES CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(C2)c2ncnc(OCC(C)(C)O)c2Cl)cc1 |r| Show InChI InChI=1S/C23H31ClN4O4/c1-5-25-21(29)15(2)16-6-8-17(9-7-16)32-18-10-11-28(12-18)20-19(24)22(27-14-26-20)31-13-23(3,4)30/h6-9,14-15,18,30H,5,10-13H2,1-4H3,(H,25,29)/t15?,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 [129-967] (Homo sapiens (Human))	BDBM212626 (BDBM212745 | US9278954, 1.17) Show SMILES CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(C2)c2ncnc(OCC(C)(C)O)c2Cl)cc1 |r| Show InChI InChI=1S/C23H31ClN4O4/c1-5-25-21(29)15(2)16-6-8-17(9-7-16)32-18-10-11-28(12-18)20-19(24)22(27-14-26-20)31-13-23(3,4)30/h6-9,14-15,18,30H,5,10-13H2,1-4H3,(H,25,29)/t15?,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	95	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair