BDBM213233 Telomestatin (TMS)
SMILES: [H]C12CSC(=N1)c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1coc(n1)-c1nc(oc1C)-c1nc2oc1C
InChI Key: InChIKey=YVSQVYZBDXIXCC-UHFFFAOYSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fe-S helicase (FANCJ) (Homo sapiens (Human)) | BDBM213233 (Telomestatin (TMS)) | UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | 8.0 | n/a |
National Institutes of Health, National Institutes of Health Biomedical Research Center | Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat... | J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fe-S helicase (FANCJ) (Homo sapiens (Human)) | BDBM213233 (Telomestatin (TMS)) | UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | 8.0 | n/a |
National Institutes of Health, National Institutes of Health Biomedical Research Center | Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat... | J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-damage-inducible protein G (DinG) (Escherichia coli (Enterobacteria)) | BDBM213233 (Telomestatin (TMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 8.0 | n/a |
National Institutes of Health, National Institutes of Health Biomedical Research Center | Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat... | J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-damage-inducible protein G (DinG) (Escherichia coli (Enterobacteria)) | BDBM213233 (Telomestatin (TMS)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | 8.0 | n/a |
National Institutes of Health, National Institutes of Health Biomedical Research Center | Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat... | J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fe-S helicase (FANCJ) (Homo sapiens (Human)) | BDBM213233 (Telomestatin (TMS)) | UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 8.0 | n/a |
National Institutes of Health, National Institutes of Health Biomedical Research Center | Assay Description Standard helicase reaction mixtures (20μl) containing 5 fmol of the indicated TP-G4 or OX-1-G2' DNA substrates or forked duplex DNA substrat... | J Biol Chem 288: 28217-29 (2013) Article DOI: 10.1074/jbc.M113.496463 BindingDB Entry DOI: 10.7270/Q2FT8JVS | |||||||||||
More data for this Ligand-Target Pair |