null

SMILES: CN[C@H](C)C(=O)Nc1cc(cc(n1)C#Cc1ccc2n(C)c(=O)ccc2c1)-c1nc(C)nc2c(C)nn(C)c12

InChI Key: InChIKey=NJZSVYYBBZWHGJ-QGZVFWFLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 213380   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Baculoviral IAP repeat-containing protein 2 [256-363] (Homo sapiens (Human))	BDBM213380 (US9278978, 15) Show SMILES CN[C@H](C)C(=O)Nc1cc(cc(n1)C#Cc1ccc2n(C)c(=O)ccc2c1)-c1nc(C)nc2c(C)nn(C)c12 |r| Show InChI InChI=1S/C29H28N8O2/c1-16-26-28(37(6)35-16)27(32-18(3)31-26)21-14-22(33-24(15-21)34-29(39)17(2)30-4)10-7-19-8-11-23-20(13-19)9-12-25(38)36(23)5/h8-9,11-15,17,30H,1-6H3,(H,33,34,39)/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% TritonX100) for one...				US Patent US9278978 (2016) BindingDB Entry DOI: 10.7270/Q2JM28G4
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM213380 (US9278978, 15) Show SMILES CN[C@H](C)C(=O)Nc1cc(cc(n1)C#Cc1ccc2n(C)c(=O)ccc2c1)-c1nc(C)nc2c(C)nn(C)c12 |r| Show InChI InChI=1S/C29H28N8O2/c1-16-26-28(37(6)35-16)27(32-18(3)31-26)21-14-22(33-24(15-21)34-29(39)17(2)30-4)10-7-19-8-11-23-20(13-19)9-12-25(38)36(23)5/h8-9,11-15,17,30H,1-6H3,(H,33,34,39)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	247	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% TritonX100) for one...				US Patent US9278978 (2016) BindingDB Entry DOI: 10.7270/Q2JM28G4
					More data for this Ligand-Target Pair