BDBM21355 2-{1-[(5-bromothiophene-2-)sulfonyl]-1H-indol-3-yl}ethan-1-amine::thiophene sulfonyltryptamine, 11n

SMILES: NCCc1cn(c2ccccc12)S(=O)(=O)c1ccc(Br)s1

InChI Key: InChIKey=HZYPTAOCUMMUQM-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM21355 (2-{1-[(5-bromothiophene-2-)sulfonyl]-1H-indol-3-yl...) Show SMILES NCCc1cn(c2ccccc12)S(=O)(=O)c1ccc(Br)s1 Show InChI InChI=1S/C14H13BrN2O2S2/c15-13-5-6-14(20-13)21(18,19)17-9-10(7-8-16)11-3-1-2-4-12(11)17/h1-6,9H,7-8,16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7	-11.0	n/a	n/a	54	n/a	n/a	7.4	22
Wyeth Research					Assay Description IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...				J Med Chem 50: 5535-8 (2007) Article DOI: 10.1021/jm070521y BindingDB Entry DOI: 10.7270/Q23R0R5G
					More data for this Ligand-Target Pair