BDBM21360 7-ethoxy-3H-phenoxazin-3-one::7-ethoxyresorufin::Ethoxyresorufin::US9216974, Ethoxy-resorufin
SMILES: CCOc1ccc2nc3ccc(=O)cc3oc2c1
InChI Key: InChIKey=CRCWUBLTFGOMDD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta amyloid A4 protein (Homo sapiens (Human)) | BDBM21360 (7-ethoxy-3H-phenoxazin-3-one | 7-ethoxyresorufin |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents | US Patent | 262 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
WASHINGTON UNIVERSITY US Patent | Assay Description To determine the Ki values, fixed brain tissues prepared from 15-month-old Tg2576 mice (N=5) will be incubated for 30 min with 1 μM methoxy-X34 ... | US Patent US9216974 (2015) BindingDB Entry DOI: 10.7270/Q2WD3ZCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A (Homo sapiens (Human)) | BDBM21360 (7-ethoxy-3H-phenoxazin-3-one | 7-ethoxyresorufin |...) | PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL | Assay Description Inhibition of human CYP1A2 | J Med Chem 53: 7129-39 (2010) Article DOI: 10.1021/jm100832d BindingDB Entry DOI: 10.7270/Q2CJ8DQZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A (Homo sapiens (Human)) | BDBM21360 (7-ethoxy-3H-phenoxazin-3-one | 7-ethoxyresorufin |...) | PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL | Assay Description Inhibition of human CYP1A2 | J Med Chem 53: 374-91 (2010) Article DOI: 10.1021/jm901319p BindingDB Entry DOI: 10.7270/Q2WQ03X8 | |||||||||||
More data for this Ligand-Target Pair |