BDBM21380 6-[4-(2-butylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::Piperazinehexanamide derivative, 18

SMILES: CCCCc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1

InChI Key: InChIKey=GLAJHBSVLZCXST-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21380   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM21380 (6-[4-(2-butylphenyl)piperazin-1-yl]-N-(1,2,3,4-tet...) Show SMILES CCCCc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 Show InChI InChI=1S/C30H43N3O/c1-2-3-12-26-14-7-9-18-29(26)33-23-21-32(22-24-33)20-10-4-5-19-30(34)31-28-17-11-15-25-13-6-8-16-27(25)28/h6-9,13-14,16,18,28H,2-5,10-12,15,17,19-24H2,1H3,(H,31,34)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari					Assay Description IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...				J Med Chem 50: 4214-21 (2007) Article DOI: 10.1021/jm070487n BindingDB Entry DOI: 10.7270/Q20000CJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM21380 (6-[4-(2-butylphenyl)piperazin-1-yl]-N-(1,2,3,4-tet...) Show SMILES CCCCc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 Show InChI InChI=1S/C30H43N3O/c1-2-3-12-26-14-7-9-18-29(26)33-23-21-32(22-24-33)20-10-4-5-19-30(34)31-28-17-11-15-25-13-6-8-16-27(25)28/h6-9,13-14,16,18,28H,2-5,10-12,15,17,19-24H2,1H3,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari					Assay Description IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...				J Med Chem 50: 4214-21 (2007) Article DOI: 10.1021/jm070487n BindingDB Entry DOI: 10.7270/Q20000CJ
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM21380 (6-[4-(2-butylphenyl)piperazin-1-yl]-N-(1,2,3,4-tet...) Show SMILES CCCCc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1 Show InChI InChI=1S/C30H43N3O/c1-2-3-12-26-14-7-9-18-29(26)33-23-21-32(22-24-33)20-10-4-5-19-30(34)31-28-17-11-15-25-13-6-8-16-27(25)28/h6-9,13-14,16,18,28H,2-5,10-12,15,17,19-24H2,1H3,(H,31,34)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.81E+3	-7.87	n/a	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Bari					Assay Description IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...				J Med Chem 50: 4214-21 (2007) Article DOI: 10.1021/jm070487n BindingDB Entry DOI: 10.7270/Q20000CJ
					More data for this Ligand-Target Pair