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SMILES: OC(=O)c1cc2ccc(cc2oc1=O)N(Cc1ccc2OCOc2c1)Cc1ccc2OCOc2c1

InChI Key: InChIKey=JDYUAPKUEHRILP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214705   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Monocarboxylate transporter 1


(Rattus norvegicus (Rat))		BDBM214705
PNG
(US9296728, 29)
Show SMILES OC(=O)c1cc2ccc(cc2oc1=O)N(Cc1ccc2OCOc2c1)Cc1ccc2OCOc2c1
Show InChI InChI=1S/C26H19NO8/c28-25(29)19-9-17-3-4-18(10-22(17)35-26(19)30)27(11-15-1-5-20-23(7-15)33-13-31-20)12-16-2-6-21-24(8-16)34-14-32-21/h1-10H,11-14H2,(H,28,29)
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 110n/an/an/an/a7.4337



Regents of the University of Minnesota

US Patent


Assay Description
The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...

US Patent US9296728 (2016)


BindingDB Entry DOI: 10.7270/Q2KH0M5R
More data for this
Ligand-Target Pair