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SMILES: O=C1N(Cc2nc3ccccc3[nH]2)C(=S)S\C1=C/c1ccc(o1)-c1ccc(cc1)-n1cccc1

InChI Key: InChIKey=NWMFAMAVUYQZGI-HAHDFKILSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214741   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Microtubule-associated protein


(Homo sapiens (Human))		BDBM214741
PNG
(Rhodanines, 29A)
Show SMILES O=C1N(Cc2nc3ccccc3[nH]2)C(=S)S\C1=C/c1ccc(o1)-c1ccc(cc1)-n1cccc1
Show InChI InChI=1S/C26H18N4O2S2/c31-25-23(34-26(33)30(25)16-24-27-20-5-1-2-6-21(20)28-24)15-19-11-12-22(32-19)17-7-9-18(10-8-17)29-13-3-4-14-29/h1-15H,16H2,(H,27,28)/b23-15-
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 540n/an/an/an/a7.4n/a



The Ohio State University



Assay Description
The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...

J Biol Chem 288: 32599-611 (2013)


Article DOI: 10.1074/jbc.M113.503474
BindingDB Entry DOI: 10.7270/Q2R49PMK
More data for this
Ligand-Target Pair