BDBM214745 Rhodanines, 33A

SMILES: [O-]C(=O)Cc1ccc(CN2C(=S)S\C(=C/c3ccc(o3)-c3ccc(cc3)-c3ccccc3)C2=O)cc1

InChI Key: InChIKey=UNPNBEGSDCHURJ-ONUIUJJFSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214745   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (TAU)(2N4R) (Homo sapiens (Human))	BDBM214745 (Rhodanines, 33A) Show SMILES [O-]C(=O)Cc1ccc(CN2C(=S)S\C(=C/c3ccc(o3)-c3ccc(cc3)-c3ccccc3)C2=O)cc1 Show InChI InChI=1S/C29H21NO4S2/c31-27(32)16-19-6-8-20(9-7-19)18-30-28(33)26(36-29(30)35)17-24-14-15-25(34-24)23-12-10-22(11-13-23)21-4-2-1-3-5-21/h1-15,17H,16,18H2,(H,31,32)/p-1/b26-17-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	7.4	n/a
The Ohio State University					Assay Description The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...				J Biol Chem 288: 32599-611 (2013) Article DOI: 10.1074/jbc.M113.503474 BindingDB Entry DOI: 10.7270/Q2R49PMK
					More data for this Ligand-Target Pair