BDBM214747 Rhodanines, 35A

SMILES: [O-]C(=O)Cc1ccc(CN2C(=S)S\C(=C/c3ccc(o3)-c3ccc(cc3)-n3cccc3)C2=O)cc1

InChI Key: InChIKey=GKTJSEYOYMHJHV-JLPGSUDCSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (TAU)(2N4R) (Homo sapiens (Human))	BDBM214747 (Rhodanines, 35A) Show SMILES [O-]C(=O)Cc1ccc(CN2C(=S)S\C(=C/c3ccc(o3)-c3ccc(cc3)-n3cccc3)C2=O)cc1 Show InChI InChI=1S/C27H20N2O4S2/c30-25(31)15-18-3-5-19(6-4-18)17-29-26(32)24(35-27(29)34)16-22-11-12-23(33-22)20-7-9-21(10-8-20)28-13-1-2-14-28/h1-14,16H,15,17H2,(H,30,31)/p-1/b24-16-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	7.4	n/a
The Ohio State University					Assay Description The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...				J Biol Chem 288: 32599-611 (2013) Article DOI: 10.1074/jbc.M113.503474 BindingDB Entry DOI: 10.7270/Q2R49PMK
					More data for this Ligand-Target Pair