BDBM214749 Rhodanines, 37A

SMILES: [O-]C(=O)CCCN1C(=S)S\C(=C/c2ccc(o2)-c2ccc(cc2)-c2ccccc2)C1=O

InChI Key: InChIKey=HEOVKECCYYUUGS-QNGOZBTKSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214749   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (TAU)(2N4R) (Homo sapiens (Human))	BDBM214749 (Rhodanines, 37A) Show SMILES [O-]C(=O)CCCN1C(=S)S\C(=C/c2ccc(o2)-c2ccc(cc2)-c2ccccc2)C1=O Show InChI InChI=1S/C24H19NO4S2/c26-22(27)7-4-14-25-23(28)21(31-24(25)30)15-19-12-13-20(29-19)18-10-8-17(9-11-18)16-5-2-1-3-6-16/h1-3,5-6,8-13,15H,4,7,14H2,(H,26,27)/p-1/b21-15-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	7.4	n/a
The Ohio State University					Assay Description The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...				J Biol Chem 288: 32599-611 (2013) Article DOI: 10.1074/jbc.M113.503474 BindingDB Entry DOI: 10.7270/Q2R49PMK
					More data for this Ligand-Target Pair