BDBM214753 Rhodanines, 41A

SMILES: O=C1N(Cc2nc3ccccc3[nH]2)C(=S)S\C1=C/c1ccc(o1)-c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=MKBSVGQEYKCEPT-XYGWBWBKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214753   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (TAU)(2N4R) (Homo sapiens (Human))	BDBM214753 (Rhodanines, 41A) Show SMILES O=C1N(Cc2nc3ccccc3[nH]2)C(=S)S\C1=C/c1ccc(o1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C28H19N3O2S2/c32-27-25(35-28(34)31(27)17-26-29-22-8-4-5-9-23(22)30-26)16-21-14-15-24(33-21)20-12-10-19(11-13-20)18-6-2-1-3-7-18/h1-16H,17H2,(H,29,30)/b25-16-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	7.4	n/a
The Ohio State University					Assay Description The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...				J Biol Chem 288: 32599-611 (2013) Article DOI: 10.1074/jbc.M113.503474 BindingDB Entry DOI: 10.7270/Q2R49PMK
					More data for this Ligand-Target Pair