null

SMILES: CC(N1C(=S)S\C(=C/c2ccc(o2)-c2cccc(Cl)c2)C1=O)C([O-])=O

InChI Key: InChIKey=GZIZWJRDLLUMPI-ZSOIEALJSA-M

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 214754   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein (Homo sapiens (Human))	BDBM214754 (Rhodanines, 42A | Rhodanines, 50A) Show SMILES CC(N1C(=S)S\C(=C/c2ccc(o2)-c2cccc(Cl)c2)C1=O)C([O-])=O Show InChI InChI=1S/C17H12ClNO4S2/c1-9(16(21)22)19-15(20)14(25-17(19)24)8-12-5-6-13(23-12)10-3-2-4-11(18)7-10/h2-9H,1H3,(H,21,22)/p-1/b14-8-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.36E+3	n/a	n/a	n/a	n/a	7.4	n/a
The Ohio State University					Assay Description The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...				J Biol Chem 288: 32599-611 (2013) Article DOI: 10.1074/jbc.M113.503474 BindingDB Entry DOI: 10.7270/Q2R49PMK
					More data for this Ligand-Target Pair
Microtubule-associated protein (Homo sapiens (Human))	BDBM214754 (Rhodanines, 42A | Rhodanines, 50A) Show SMILES CC(N1C(=S)S\C(=C/c2ccc(o2)-c2cccc(Cl)c2)C1=O)C([O-])=O Show InChI InChI=1S/C17H12ClNO4S2/c1-9(16(21)22)19-15(20)14(25-17(19)24)8-12-5-6-13(23-12)10-3-2-4-11(18)7-10/h2-9H,1H3,(H,21,22)/p-1/b14-8-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	7.4	n/a
The Ohio State University					Assay Description The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...				J Biol Chem 288: 32599-611 (2013) Article DOI: 10.1074/jbc.M113.503474 BindingDB Entry DOI: 10.7270/Q2R49PMK
					More data for this Ligand-Target Pair