BDBM214755 Rhodanines, 43A

SMILES: O=C1N(CCc2c[nH]cn2)C(=S)S\C1=C/c1ccc(o1)-c1ccc(cc1)-n1cccc1

InChI Key: InChIKey=LNJGDLJZRRYUOP-BKUYFWCQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (TAU)(2N4R) (Homo sapiens (Human))	BDBM214755 (Rhodanines, 43A) Show SMILES O=C1N(CCc2c[nH]cn2)C(=S)S\C1=C/c1ccc(o1)-c1ccc(cc1)-n1cccc1 Show InChI InChI=1S/C23H18N4O2S2/c28-22-21(31-23(30)27(22)12-9-17-14-24-15-25-17)13-19-7-8-20(29-19)16-3-5-18(6-4-16)26-10-1-2-11-26/h1-8,10-11,13-15H,9,12H2,(H,24,25)/b21-13-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	7.4	n/a
The Ohio State University					Assay Description The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...				J Biol Chem 288: 32599-611 (2013) Article DOI: 10.1074/jbc.M113.503474 BindingDB Entry DOI: 10.7270/Q2R49PMK
					More data for this Ligand-Target Pair