BDBM214766 Rhodanines, 54A

SMILES: O=C1N(CCc2c[nH]cn2)C(=S)S\C1=C/c1ccc(o1)-c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=KHFUSJDMUDNWOL-UCQKPKSFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microtubule-associated protein tau (TAU)(2N4R) (Homo sapiens (Human))	BDBM214766 (Rhodanines, 54A) Show SMILES O=C1N(CCc2c[nH]cn2)C(=S)S\C1=C/c1ccc(o1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C25H19N3O2S2/c29-24-23(32-25(31)28(24)13-12-20-15-26-16-27-20)14-21-10-11-22(30-21)19-8-6-18(7-9-19)17-4-2-1-3-5-17/h1-11,14-16H,12-13H2,(H,26,27)/b23-14-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	7.4	n/a
The Ohio State University					Assay Description The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...				J Biol Chem 288: 32599-611 (2013) Article DOI: 10.1074/jbc.M113.503474 BindingDB Entry DOI: 10.7270/Q2R49PMK
					More data for this Ligand-Target Pair