BDBM214800 N-methylscopolamine (NMS)

SMILES: C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1

InChI Key: InChIKey=LZCOQTDXKCNBEE-XJMZPCNVSA-N

Data: 22 Kd

PDB links: 4 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 214800   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
M3 muscarinic receptor (M3'(3C)-Xa) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.403	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa T556C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a
National Institutes of Health					Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa A177C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.521	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa K178C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.499	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa R179C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.493	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa T180C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.751	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.555	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa K548C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.555	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa T549C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.564	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa F550C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.556	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa R551C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.524	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa T552C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.438	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa T553C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.548	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa F554C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.583	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa K555C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.553	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa T556C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.462	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a
National Institutes of Health					Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa R176C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a
National Institutes of Health					Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa T180C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	1.11	n/a	n/a	n/a	n/a	n/a
National Institutes of Health					Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa F550C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	1.15	n/a	n/a	n/a	n/a	n/a
National Institutes of Health					Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa T553C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	1.02	n/a	n/a	n/a	n/a	n/a
National Institutes of Health					Assay Description In brief, membranes from COS-7 cells expressing different Cys-substituted mutant M3R constructs were first treated with CuPhen (100 μM; 10 min a...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair
M3 muscarinic receptor (M3'(3C)-Xa R176C) (Rattus norvegicus (Rat))	BDBM214800 (N-methylscopolamine (NMS)) Show SMILES C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1 Show InChI InChI=1S/C18H24NO4/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11/h3-7,12-17,20H,8-10H2,1-2H3/q+1/t12?,13-,14-,15+,16-,17+/m1/s1	GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	0.484	n/a	n/a	n/a	7.4	n/a
National Institutes of Health					Assay Description In brief, binding reactions containing ~10 μg of membrane protein per tube were carried out for 2 h (22 °C) in 1 ml of binding buffer containing...				J Biol Chem 288: 34777-90 (2013) Article DOI: 10.1074/jbc.M113.503714 BindingDB Entry DOI: 10.7270/Q2JH3K1C
					More data for this Ligand-Target Pair