BDBM21533 N-[(2R,3R,4R,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-methoxy-5-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-3-yl]acetamide::Thioureido N-acetyllactosamine derivative, 17
SMILES: CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1NC(C)=O
InChI Key: InChIKey=PKPZITUQXLANSE-AEBMIEDASA-N
Data: 11 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Galectin-1 (Homo sapiens (Human)) | BDBM21533 (N-[(2R,3R,4R,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 7.00E+4 | n/a | n/a | n/a | 7.2 | 24 |
Lund University | Assay Description In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the... | Bioorg Med Chem 14: 1215-20 (2006) Article DOI: 10.1016/j.bmc.2005.09.050 BindingDB Entry DOI: 10.7270/Q2B856FP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM21533 (N-[(2R,3R,4R,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 6.70E+4 | n/a | n/a | n/a | 7.2 | 24 |
Lund University | Assay Description In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the... | Bioorg Med Chem 14: 1215-20 (2006) Article DOI: 10.1016/j.bmc.2005.09.050 BindingDB Entry DOI: 10.7270/Q2B856FP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-7 (Homo sapiens (Human)) | BDBM21533 (N-[(2R,3R,4R,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.90E+5 | n/a | n/a | n/a | n/a | n/a |
Lund University | Assay Description In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the... | Bioorg Med Chem 14: 1215-20 (2006) Article DOI: 10.1016/j.bmc.2005.09.050 BindingDB Entry DOI: 10.7270/Q2B856FP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-8 (Homo sapiens (Human)) | BDBM21533 (N-[(2R,3R,4R,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 7.00E+5 | n/a | n/a | n/a | n/a | n/a |
Lund University | Assay Description In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the... | Bioorg Med Chem 14: 1215-20 (2006) Article DOI: 10.1016/j.bmc.2005.09.050 BindingDB Entry DOI: 10.7270/Q2B856FP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-9 (Homo sapiens (Human)) | BDBM21533 (N-[(2R,3R,4R,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 5.00E+5 | n/a | n/a | n/a | n/a | n/a |
Lund University | Assay Description In fluorescence polarization measurements, a fluorescent probe was excited with plane-polarized light and the degree of polarization remaining in the... | Bioorg Med Chem 14: 1215-20 (2006) Article DOI: 10.1016/j.bmc.2005.09.050 BindingDB Entry DOI: 10.7270/Q2B856FP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM21533 (N-[(2R,3R,4R,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 5.90E+4 | n/a | n/a | n/a | n/a | n/a |
The Hashemite University Curated by ChEMBL | Assay Description Binding affinity to human galectin 3 at 20 degC by competitive fluorescence polarization assay | Bioorg Med Chem 18: 5367-78 (2010) Article DOI: 10.1016/j.bmc.2010.05.040 BindingDB Entry DOI: 10.7270/Q2FQ9XMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-1 (Homo sapiens (Human)) | BDBM21533 (N-[(2R,3R,4R,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 7.00E+4 | n/a | n/a | n/a | n/a | n/a |
Utrecht University Curated by ChEMBL | Assay Description Binding affinity to galectin-1 (unknown origin) by fluorescence polarization assay | J Med Chem 56: 1350-4 (2013) Article DOI: 10.1021/jm301677r BindingDB Entry DOI: 10.7270/Q2NK3GBS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-7 (Homo sapiens (Human)) | BDBM21533 (N-[(2R,3R,4R,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 5.50E+6 | n/a | n/a | n/a | n/a | n/a |
The Hashemite University Curated by ChEMBL | Assay Description Binding affinity to human galectin 7 at 4 degC by competitive fluorescence polarization assay | Bioorg Med Chem 18: 5367-78 (2010) Article DOI: 10.1016/j.bmc.2010.05.040 BindingDB Entry DOI: 10.7270/Q2FQ9XMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-8 (Homo sapiens (Human)) | BDBM21533 (N-[(2R,3R,4R,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.00E+6 | n/a | n/a | n/a | n/a | n/a |
The Hashemite University Curated by ChEMBL | Assay Description Binding affinity to human galectin 8 N-terminal domain at 20 degC by competitive fluorescence polarization assay | Bioorg Med Chem 18: 5367-78 (2010) Article DOI: 10.1016/j.bmc.2010.05.040 BindingDB Entry DOI: 10.7270/Q2FQ9XMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-9 (Homo sapiens (Human)) | BDBM21533 (N-[(2R,3R,4R,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.90E+5 | n/a | n/a | n/a | n/a | n/a |
The Hashemite University Curated by ChEMBL | Assay Description Binding affinity to human galectin 9 N-terminal domain at 20 degC by competitive fluorescence polarization assay | Bioorg Med Chem 18: 5367-78 (2010) Article DOI: 10.1016/j.bmc.2010.05.040 BindingDB Entry DOI: 10.7270/Q2FQ9XMJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Galectin-3 (Homo sapiens (Human)) | BDBM21533 (N-[(2R,3R,4R,5S,6R)-4-hydroxy-6-(hydroxymethyl)-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a |
Utrecht University Curated by ChEMBL | Assay Description Binding affinity to galectin-3 (unknown origin) by fluorescence polarization assay | J Med Chem 56: 1350-4 (2013) Article DOI: 10.1021/jm301677r BindingDB Entry DOI: 10.7270/Q2NK3GBS | |||||||||||
More data for this Ligand-Target Pair |