BDBM215620 US9296745, 184

SMILES: FC1(F)CCN(C1)C(=O)[C@@H]1CCCN(C1)c1ccc2nc([nH]c2n1)-c1cccc(n1)C1CC1

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 215620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM215620 (US9296745, 184) Show SMILES FC1(F)CCN(C1)C(=O)[C@@H]1CCCN(C1)c1ccc2nc([nH]c2n1)-c1cccc(n1)C1CC1 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.2	n/a	n/a	n/a	n/a	7.4	25
Pfizer Inc. US Patent					Assay Description For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...				US Patent US9296745 (2016) BindingDB Entry DOI: 10.7270/Q25719VW
					More data for this Ligand-Target Pair