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BDBM21622 2-methyl-5-(1H-pyrazol-5-yl)pyridine::Pyridine, 10

SMILES: Cc1ccc(cn1)-c1cc[nH]n1

InChI Key: InChIKey=FOYWCEUVVIHJKD-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21622   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin D Synthase


(Homo sapiens (human))
BDBM21622
PNG
(2-methyl-5-(1H-pyrazol-5-yl)pyridine | Pyridine, 1...)
Show SMILES Cc1ccc(cn1)-c1cc[nH]n1
Show InChI InChI=1S/C9H9N3/c1-7-2-3-8(6-10-7)9-4-5-11-12-9/h2-6H,1H3,(H,11,12)
PDB
MMDB

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Article
PubMed
n/an/a 3.47E+4n/an/an/an/a7.222



AstraZeneca



Assay Description
The PGDS glutathione-S-transferase (GST) activity was measured by using MonoChloroBimane (MCB) as a chromogenic substrate. The assay was run at 384-w...


J Med Chem 51: 2178-86 (2008)

More data for this
Ligand-Target Pair