null

SMILES: COc1cc(ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1)-c1nc(C)cs1

InChI Key: InChIKey=RBXZTMZEWIAWOY-SFHVURJKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 21788   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM21788 (2-[(1S)-5-{3-[2-methoxy-4-(4-methyl-1,3-thiazol-2-...) Show SMILES COc1cc(ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1)-c1nc(C)cs1 |r| Show InChI InChI=1S/C25H27NO5S/c1-16-15-32-25(26-16)19-6-9-22(23(13-19)29-2)31-11-3-10-30-20-7-8-21-17(12-20)4-5-18(21)14-24(27)28/h6-9,12-13,15,18H,3-5,10-11,14H2,1-2H3,(H,27,28)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	268	n/a	n/a	n/a	25
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...				J Med Chem 50: 984-1000 (2007) Article DOI: 10.1021/jm061299k BindingDB Entry DOI: 10.7270/Q2NK3C93
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM21788 (2-[(1S)-5-{3-[2-methoxy-4-(4-methyl-1,3-thiazol-2-...) Show SMILES COc1cc(ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1)-c1nc(C)cs1 |r| Show InChI InChI=1S/C25H27NO5S/c1-16-15-32-25(26-16)19-6-9-22(23(13-19)29-2)31-11-3-10-30-20-7-8-21-17(12-20)4-5-18(21)14-24(27)28/h6-9,12-13,15,18H,3-5,10-11,14H2,1-2H3,(H,27,28)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	25
Bayer HealthCare Pharmaceuticals Corporation					Assay Description Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...				J Med Chem 50: 984-1000 (2007) Article DOI: 10.1021/jm061299k BindingDB Entry DOI: 10.7270/Q2NK3C93
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM21788 (2-[(1S)-5-{3-[2-methoxy-4-(4-methyl-1,3-thiazol-2-...) Show SMILES COc1cc(ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1)-c1nc(C)cs1 |r| Show InChI InChI=1S/C25H27NO5S/c1-16-15-32-25(26-16)19-6-9-22(23(13-19)29-2)31-11-3-10-30-20-7-8-21-17(12-20)4-5-18(21)14-24(27)28/h6-9,12-13,15,18H,3-5,10-11,14H2,1-2H3,(H,27,28)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	1.05E+6	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at Homo sapiens (human) PPARgamma expressed in mouse 3T3-L1 cells incubated for 2 days followed by compound wash out measured after ...				Citation and Details Article DOI: 10.1007/s00044-011-9599-z BindingDB Entry DOI: 10.7270/Q22J6FR8
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM21788 (2-[(1S)-5-{3-[2-methoxy-4-(4-methyl-1,3-thiazol-2-...) Show SMILES COc1cc(ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1)-c1nc(C)cs1 |r| Show InChI InChI=1S/C25H27NO5S/c1-16-15-32-25(26-16)19-6-9-22(23(13-19)29-2)31-11-3-10-30-20-7-8-21-17(12-20)4-5-18(21)14-24(27)28/h6-9,12-13,15,18H,3-5,10-11,14H2,1-2H3,(H,27,28)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	3.70E+8	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at GST-tagged Homo sapiens (human) PPARdelta ligand binding domain after 2 hr by FRET assay				Citation and Details Article DOI: 10.1007/s00044-011-9599-z BindingDB Entry DOI: 10.7270/Q22J6FR8
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM21788 (2-[(1S)-5-{3-[2-methoxy-4-(4-methyl-1,3-thiazol-2-...) Show SMILES COc1cc(ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1)-c1nc(C)cs1 |r| Show InChI InChI=1S/C25H27NO5S/c1-16-15-32-25(26-16)19-6-9-22(23(13-19)29-2)31-11-3-10-30-20-7-8-21-17(12-20)4-5-18(21)14-24(27)28/h6-9,12-13,15,18H,3-5,10-11,14H2,1-2H3,(H,27,28)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	3.73E+6	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at GST-tagged Homo sapiens (human) PPARalpha ligand binding domain after 2 hr by FRET assay				Citation and Details Article DOI: 10.1007/s00044-011-9599-z BindingDB Entry DOI: 10.7270/Q22J6FR8
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM21788 (2-[(1S)-5-{3-[2-methoxy-4-(4-methyl-1,3-thiazol-2-...) Show SMILES COc1cc(ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1)-c1nc(C)cs1 |r| Show InChI InChI=1S/C25H27NO5S/c1-16-15-32-25(26-16)19-6-9-22(23(13-19)29-2)31-11-3-10-30-20-7-8-21-17(12-20)4-5-18(21)14-24(27)28/h6-9,12-13,15,18H,3-5,10-11,14H2,1-2H3,(H,27,28)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	960	n/a	n/a	n/a	25
Bayer HealthCare Pharmaceuticals Corporation					Assay Description PPAR gamma activity was assessed by using the IRBA in mouse 3T3-L1 cells. This assay measures the ability of test compound to cause an increase in th...				J Med Chem 50: 984-1000 (2007) Article DOI: 10.1021/jm061299k BindingDB Entry DOI: 10.7270/Q2NK3C93
					More data for this Ligand-Target Pair