null

SMILES: CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2CC)n2CCOCc12)c1ccccc1

InChI Key: InChIKey=LNLKPPWJJZVTLN-AZUAARDMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM218405 (US9284333, 16fc | US9884860, Example 16fc) Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2CC)n2CCOCc12)c1ccccc1 |r| Show InChI InChI=1S/C24H31N3O3/c1-3-18-11-8-12-26(18)24(29)21-15-19(22-16-30-14-13-27(21)22)23(28)25-20(4-2)17-9-6-5-7-10-17/h5-7,9-10,15,18,20H,3-4,8,11-14,16H2,1-2H3,(H,25,28)/t18-,20+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9884860 (2018) BindingDB Entry DOI: 10.7270/Q2862JGT
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM218405 (US9284333, 16fc | US9884860, Example 16fc) Show SMILES CC[C@@H](NC(=O)c1cc(C(=O)N2CCC[C@@H]2CC)n2CCOCc12)c1ccccc1 |r| Show InChI InChI=1S/C24H31N3O3/c1-3-18-11-8-12-26(18)24(29)21-15-19(22-16-30-14-13-27(21)22)23(28)25-20(4-2)17-9-6-5-7-10-17/h5-7,9-10,15,18,20H,3-4,8,11-14,16H2,1-2H3,(H,25,28)/t18-,20+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9284333 (2016) BindingDB Entry DOI: 10.7270/Q2FJ2FMC
					More data for this Ligand-Target Pair