Found 4 hits for monomerid = 218897 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Casein kinase II subunit alpha/beta
(Homo sapiens (Human)-Rattus norvegicus) | BDBM218897
(US9303033, E3, Table 10A, Compound 5 | US9303033, ...)Show SMILES CS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 |r,wU:5.4,wD:8.11,(-9.03,3.45,;-7.49,3.45,;-7.49,4.99,;-6.15,4.22,;-7.49,1.91,;-6.15,1.14,;-4.82,1.91,;-3.48,1.14,;-3.48,-.4,;-4.82,-1.17,;-6.15,-.4,;-2.15,-1.17,;-.82,-.4,;-.82,1.14,;.52,1.91,;.52,3.45,;1.85,4.22,;3.39,4.22,;2.62,5.56,;1.85,1.14,;3.31,1.62,;4.22,.37,;3.31,-.87,;3.71,-2.36,;5.2,-2.76,;6.45,-1.85,;7.69,-2.76,;9.03,-1.99,;7.22,-4.22,;5.68,-4.22,;4.91,-5.56,;1.85,-.4,;.52,-1.17,)| Show InChI InChI=1S/C20H26N8O4S/c1-33(31,32)27-14-6-4-12(5-7-14)22-16-9-17(23-13-2-3-13)28-18(25-16)11(10-21-28)8-15-19(29)26-20(30)24-15/h8-10,12-14,23,27H,2-7H2,1H3,(H,22,25)(H2,24,26,29,30)/b15-8-/t12-,14- | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | 7.2 | n/a |
SENHWA BIOSCIENCES, INC.
US Patent
| Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ... |
US Patent US9303033 (2016)
BindingDB Entry DOI: 10.7270/Q2CN72RX |
More data for this Ligand-Target Pair | |
Casein kinase II subunit beta
(Homo sapiens (Human)) | BDBM218897
(US9303033, E3, Table 10A, Compound 5 | US9303033, ...)Show SMILES CS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 |r,wU:5.4,wD:8.11,(-9.03,3.45,;-7.49,3.45,;-7.49,4.99,;-6.15,4.22,;-7.49,1.91,;-6.15,1.14,;-4.82,1.91,;-3.48,1.14,;-3.48,-.4,;-4.82,-1.17,;-6.15,-.4,;-2.15,-1.17,;-.82,-.4,;-.82,1.14,;.52,1.91,;.52,3.45,;1.85,4.22,;3.39,4.22,;2.62,5.56,;1.85,1.14,;3.31,1.62,;4.22,.37,;3.31,-.87,;3.71,-2.36,;5.2,-2.76,;6.45,-1.85,;7.69,-2.76,;9.03,-1.99,;7.22,-4.22,;5.68,-4.22,;4.91,-5.56,;1.85,-.4,;.52,-1.17,)| Show InChI InChI=1S/C20H26N8O4S/c1-33(31,32)27-14-6-4-12(5-7-14)22-16-9-17(23-13-2-3-13)28-18(25-16)11(10-21-28)8-15-19(29)26-20(30)24-15/h8-10,12-14,23,27H,2-7H2,1H3,(H,22,25)(H2,24,26,29,30)/b15-8-/t12-,14- | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 476 | n/a | n/a | n/a | n/a | 7.0 | n/a |
SENHWA BIOSCIENCES, INC.
US Patent
| Assay Description Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ... |
US Patent US9303033 (2016)
BindingDB Entry DOI: 10.7270/Q2CN72RX |
More data for this Ligand-Target Pair | |
Casein kinase II subunit alpha/beta
(Homo sapiens (Human)-Rattus norvegicus) | BDBM218897
(US9303033, E3, Table 10A, Compound 5 | US9303033, ...)Show SMILES CS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 |r,wU:5.4,wD:8.11,(-9.03,3.45,;-7.49,3.45,;-7.49,4.99,;-6.15,4.22,;-7.49,1.91,;-6.15,1.14,;-4.82,1.91,;-3.48,1.14,;-3.48,-.4,;-4.82,-1.17,;-6.15,-.4,;-2.15,-1.17,;-.82,-.4,;-.82,1.14,;.52,1.91,;.52,3.45,;1.85,4.22,;3.39,4.22,;2.62,5.56,;1.85,1.14,;3.31,1.62,;4.22,.37,;3.31,-.87,;3.71,-2.36,;5.2,-2.76,;6.45,-1.85,;7.69,-2.76,;9.03,-1.99,;7.22,-4.22,;5.68,-4.22,;4.91,-5.56,;1.85,-.4,;.52,-1.17,)| Show InChI InChI=1S/C20H26N8O4S/c1-33(31,32)27-14-6-4-12(5-7-14)22-16-9-17(23-13-2-3-13)28-18(25-16)11(10-21-28)8-15-19(29)26-20(30)24-15/h8-10,12-14,23,27H,2-7H2,1H3,(H,22,25)(H2,24,26,29,30)/b15-8-/t12-,14- | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | 7.2 | n/a |
SENHWA BIOSCIENCES, INC.
US Patent
| Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ... |
US Patent US9303033 (2016)
BindingDB Entry DOI: 10.7270/Q2CN72RX |
More data for this Ligand-Target Pair | |
Casein kinase II subunit beta
(Homo sapiens (Human)) | BDBM218897
(US9303033, E3, Table 10A, Compound 5 | US9303033, ...)Show SMILES CS(=O)(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1 |r,wU:5.4,wD:8.11,(-9.03,3.45,;-7.49,3.45,;-7.49,4.99,;-6.15,4.22,;-7.49,1.91,;-6.15,1.14,;-4.82,1.91,;-3.48,1.14,;-3.48,-.4,;-4.82,-1.17,;-6.15,-.4,;-2.15,-1.17,;-.82,-.4,;-.82,1.14,;.52,1.91,;.52,3.45,;1.85,4.22,;3.39,4.22,;2.62,5.56,;1.85,1.14,;3.31,1.62,;4.22,.37,;3.31,-.87,;3.71,-2.36,;5.2,-2.76,;6.45,-1.85,;7.69,-2.76,;9.03,-1.99,;7.22,-4.22,;5.68,-4.22,;4.91,-5.56,;1.85,-.4,;.52,-1.17,)| Show InChI InChI=1S/C20H26N8O4S/c1-33(31,32)27-14-6-4-12(5-7-14)22-16-9-17(23-13-2-3-13)28-18(25-16)11(10-21-28)8-15-19(29)26-20(30)24-15/h8-10,12-14,23,27H,2-7H2,1H3,(H,22,25)(H2,24,26,29,30)/b15-8-/t12-,14- | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | >2.50E+3 | n/a | n/a | n/a | n/a | 7.0 | n/a |
SENHWA BIOSCIENCES, INC.
US Patent
| Assay Description 5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m... |
US Patent US9303033 (2016)
BindingDB Entry DOI: 10.7270/Q2CN72RX |
More data for this Ligand-Target Pair | |