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BDBM22003 5-(ethylsulfanyl)-3-methyl-1-(2-methylpropyl)-6-{[2-(trifluoromethyl)phenyl]methyl}-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione::Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 10

SMILES: CCSc1c(Cc2ccccc2C(F)(F)F)sc2n(CC(C)C)c(=O)n(C)c(=O)c12

InChI Key: InChIKey=MIAXOMOVNFGVNO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22003   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monocarboxylate Transporter 1


(Homo sapiens (Human))
BDBM22003
PNG
(5-(ethylsulfanyl)-3-methyl-1-(2-methylpropyl)-6-{[...)
Show SMILES CCSc1c(Cc2ccccc2C(F)(F)F)sc2n(CC(C)C)c(=O)n(C)c(=O)c12
Show InChI InChI=1S/C21H23F3N2O2S2/c1-5-29-17-15(10-13-8-6-7-9-14(13)21(22,23)24)30-19-16(17)18(27)25(4)20(28)26(19)11-12(2)3/h6-9,12H,5,10-11H2,1-4H3
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PC cid
PC sid
UniChem
Article
PubMed
6 -11.1n/an/an/an/an/a7.822



AstraZeneca



Assay Description
Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...


Bioorg Med Chem Lett 16: 2260-5 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.024
BindingDB Entry DOI: 10.7270/Q2C24TQK
More data for this
Ligand-Target Pair