BDBM220116 US9271961, CBM
SMILES: COc1ccc2n(cc(CNC(C)=O)c2c1)C(=O)c1ccc(Cl)cc1
InChI Key: InChIKey=MRBOZXKARHNOMR-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3) (Homo sapiens (Human)) | BDBM220116 (US9271961, CBM) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of the University of Pennsylvania US Patent | Assay Description Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ... | US Patent US9271961 (2016) BindingDB Entry DOI: 10.7270/Q27W6B22 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C1 (Homo sapiens (Human)) | BDBM220116 (US9271961, CBM) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of the University of Pennsylvania US Patent | Assay Description Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ... | US Patent US9271961 (2016) BindingDB Entry DOI: 10.7270/Q27W6B22 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C2 (Homo sapiens (Human)) | BDBM220116 (US9271961, CBM) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Trustees of the University of Pennsylvania US Patent | Assay Description Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ... | US Patent US9271961 (2016) BindingDB Entry DOI: 10.7270/Q27W6B22 | |||||||||||
More data for this Ligand-Target Pair |