BDBM22023 5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-methyl-1-(2-methylpropyl)-6-(quinolin-5-ylmethyl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione::Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 31

SMILES: CC(C)Cn1c2sc(Cc3cccc4ncccc34)c(C(=O)N3CC[C@@H](O)C3)c2c(=O)n(C)c1=O

InChI Key: InChIKey=FHYIMZUERWPLHA-QGZVFWFLSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monocarboxylate Transporter 1 (Homo sapiens (Human))	BDBM22023 (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...) Show SMILES CC(C)Cn1c2sc(Cc3cccc4ncccc34)c(C(=O)N3CC[C@@H](O)C3)c2c(=O)n(C)c1=O |r| Show InChI InChI=1S/C26H28N4O4S/c1-15(2)13-30-25-22(23(32)28(3)26(30)34)21(24(33)29-11-9-17(31)14-29)20(35-25)12-16-6-4-8-19-18(16)7-5-10-27-19/h4-8,10,15,17,31H,9,11-14H2,1-3H3/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.30	-11.2	n/a	n/a	n/a	n/a	n/a	7.4	22
AstraZeneca					Assay Description A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...				Bioorg Med Chem Lett 16: 2260-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.024 BindingDB Entry DOI: 10.7270/Q2C24TQK
					More data for this Ligand-Target Pair