BDBM220492 US9296741, 81

SMILES: CCNC(=O)c1cc2c(nn(C)c(=O)c2[nH]1)-c1cc(NS(C)(=O)=O)ccc1Oc1ccccc1

InChI Key: InChIKey=CBYYDRRKLHBXOZ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220492   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human))	BDBM220492 (US9296741, 81) Show SMILES CCNC(=O)c1cc2c(nn(C)c(=O)c2[nH]1)-c1cc(NS(C)(=O)=O)ccc1Oc1ccccc1 Show InChI InChI=1S/C23H23N5O5S/c1-4-24-22(29)18-13-17-20(26-28(2)23(30)21(17)25-18)16-12-14(27-34(3,31)32)10-11-19(16)33-15-8-6-5-7-9-15/h5-13,25,27H,4H2,1-3H3,(H,24,29)	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.990	-12.3	n/a	n/a	n/a	n/a	n/a	6.0	25
AbbVie Inc. US Patent					Assay Description A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...				US Patent US9296741 (2016) BindingDB Entry DOI: 10.7270/Q26W98ZQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4)(aa 57-168) (Homo sapiens (Human))	BDBM220492 (US9296741, 81) Show SMILES CCNC(=O)c1cc2c(nn(C)c(=O)c2[nH]1)-c1cc(NS(C)(=O)=O)ccc1Oc1ccccc1 Show InChI InChI=1S/C23H23N5O5S/c1-4-24-22(29)18-13-17-20(26-28(2)23(30)21(17)25-18)16-12-14(27-34(3,31)32)10-11-19(16)33-15-8-6-5-7-9-15/h5-13,25,27H,4H2,1-3H3,(H,24,29)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	9.5	-10.9	n/a	n/a	n/a	n/a	n/a	6.0	25
AbbVie Inc. US Patent					Assay Description A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...				US Patent US9296741 (2016) BindingDB Entry DOI: 10.7270/Q26W98ZQ
					More data for this Ligand-Target Pair