BDBM220684 US9296741, 273

SMILES: CN(C)S(=O)(=O)c1ccc(OCC2CC2)c(c1)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key: InChIKey=OBDABMYIQCEIPF-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220684   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (BRD4)(aa 57-168) (Homo sapiens (Human))	BDBM220684 (US9296741, 273) Show SMILES CN(C)S(=O)(=O)c1ccc(OCC2CC2)c(c1)-c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C20H23N3O4S/c1-22(2)28(25,26)14-6-7-18(27-12-13-4-5-13)16(10-14)17-11-23(3)20(24)19-15(17)8-9-21-19/h6-11,13,21H,4-5,12H2,1-3H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.20	-12.2	n/a	n/a	n/a	n/a	n/a	6.0	25
AbbVie Inc. US Patent					Assay Description A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...				US Patent US9296741 (2016) BindingDB Entry DOI: 10.7270/Q26W98ZQ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4)(aa 352-457) (Homo sapiens (Human))	BDBM220684 (US9296741, 273) Show SMILES CN(C)S(=O)(=O)c1ccc(OCC2CC2)c(c1)-c1cn(C)c(=O)c2[nH]ccc12 Show InChI InChI=1S/C20H23N3O4S/c1-22(2)28(25,26)14-6-7-18(27-12-13-4-5-13)16(10-14)17-11-23(3)20(24)19-15(17)8-9-21-19/h6-11,13,21H,4-5,12H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.30	-12.1	n/a	n/a	n/a	n/a	n/a	6.0	25
AbbVie Inc. US Patent					Assay Description A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...				US Patent US9296741 (2016) BindingDB Entry DOI: 10.7270/Q26W98ZQ
					More data for this Ligand-Target Pair