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SMILES: CN(C)C(=O)c1ccc(OC\C(CN)=C/F)cc1C

InChI Key: InChIKey=RIQMKFDFQPGUSV-XFFZJAGNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 220872   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM220872 (US9302986, 26) Show SMILES CN(C)C(=O)c1ccc(OC\C(CN)=C/F)cc1C Show InChI InChI=1S/C14H19FN2O2/c1-10-6-12(19-9-11(7-15)8-16)4-5-13(10)14(18)17(2)3/h4-7H,8-9,16H2,1-3H3/b11-7-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	7.4	37
BOEHRINGER INGELHEIM INTERNATIONAL GMBH US Patent					Assay Description Recombinant human MAO-B (0.06 mg/mL; Sigma Aldrich) was used as source of MAO-B enzyme activities. The assay was performed in a similar way as for hu...				US Patent US9302986 (2016) BindingDB Entry DOI: 10.7270/Q2ZC81QZ
					More data for this Ligand-Target Pair
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human))	BDBM220872 (US9302986, 26) Show SMILES CN(C)C(=O)c1ccc(OC\C(CN)=C/F)cc1C Show InChI InChI=1S/C14H19FN2O2/c1-10-6-12(19-9-11(7-15)8-16)4-5-13(10)14(18)17(2)3/h4-7H,8-9,16H2,1-3H3/b11-7-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	7.4	37
BOEHRINGER INGELHEIM INTERNATIONAL GMBH US Patent					Assay Description Recombinant human DAO (2.4 μg/mL) was used as source of DAO enzyme activities. The assay was performed as described in the method for human SSAO/V...				US Patent US9302986 (2016) BindingDB Entry DOI: 10.7270/Q2ZC81QZ
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM220872 (US9302986, 26) Show SMILES CN(C)C(=O)c1ccc(OC\C(CN)=C/F)cc1C Show InChI InChI=1S/C14H19FN2O2/c1-10-6-12(19-9-11(7-15)8-16)4-5-13(10)14(18)17(2)3/h4-7H,8-9,16H2,1-3H3/b11-7-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a	7.4	n/a
BOEHRINGER INGELHEIM INTERNATIONAL GMBH US Patent					Assay Description Briefly, HMEC cell expressing human SSAO/VAP-1 were grown in several 10 cm petri dishes, once the cells reached 100% confluency, cells were harvested...				US Patent US9302986 (2016) BindingDB Entry DOI: 10.7270/Q2ZC81QZ
					More data for this Ligand-Target Pair