BDBM220885 US9302986, 9
SMILES: NC\C(COc1ccc(cc1)S(N)(=O)=O)=C\F
InChI Key: InChIKey=GJRSZKOPZAJCGZ-YVMONPNESA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM220885 (US9302986, 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH US Patent | Assay Description Recombinant human MAO-B (0.06 mg/mL; Sigma Aldrich) was used as source of MAO-B enzyme activities. The assay was performed in a similar way as for hu... | US Patent US9302986 (2016) BindingDB Entry DOI: 10.7270/Q2ZC81QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diamine oxidase (DAO) (Homo sapiens (Human)) | BDBM220885 (US9302986, 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH US Patent | Assay Description Recombinant human DAO (2.4 μg/mL) was used as source of DAO enzyme activities. The assay was performed as described in the method for human SSAO/V... | US Patent US9302986 (2016) BindingDB Entry DOI: 10.7270/Q2ZC81QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular adhesion protein 1 (VAP-1) (Rattus norvegicus (Rat)) | BDBM220885 (US9302986, 9) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | 7.4 | n/a |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH US Patent | Assay Description Abdominal fat from BALB/c mice, Wistar or Sprague Dawley rats, which are tissues enriched with SSAO/VAP-1-were surgically removed. For every gram of ... | US Patent US9302986 (2016) BindingDB Entry DOI: 10.7270/Q2ZC81QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular adhesion protein 1 (VAP-1) (Homo sapiens (Human)) | BDBM220885 (US9302986, 9) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1.00E+5 | n/a | n/a | n/a | n/a | 7.4 | n/a |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH US Patent | Assay Description Briefly, HMEC cell expressing human SSAO/VAP-1 were grown in several 10 cm petri dishes, once the cells reached 100% confluency, cells were harvested... | US Patent US9302986 (2016) BindingDB Entry DOI: 10.7270/Q2ZC81QZ | |||||||||||
More data for this Ligand-Target Pair |